Clinically proven to promote substantial weight loss and improve cardiovascular health, Wegovy injections help control appetite and lessen food cravings.
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Wegovy is a weight loss injection intended for adults who are overweight or obese. The treatment is intended to be taken alongside a healthy, calorie-controlled diet and a regular exercise regimen, and it works by mimicking a naturally occurring hormone that regulates appetite and blood sugar levels.
The medication helps reduce hunger, support healthier eating habits and promote long-term weight loss. Each pre-filled pen is designed to be simple and discreet, enabling self-injection at home without specialised training.
Weight Loss Journey is proud to offer Wegovy pens at the following prices:
Dispensed from a Registered UK PharmacyYou can buy Wegovy weight loss injections once you’ve obtained a prescription from a specialist consultation service or a licensed prescriber. The most straightforward way to obtain the treatment is by using an online provider such as Weight Loss Journey.
We’re committed to giving you more control over your healthcare, which is why our consultation service is available at any time from your own home. No lengthy waiting times or face-to-face appointments, just a reliable and hassle-free way to get the treatment you need.
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Wegovy is a prescription-only medication given as a once-weekly injection. It contains semaglutide, a medicine which copies the effects of the body’s natural gut hormone GLP-1. Wegovy injections are among the most effective weight loss treatments available, with clinical studies showing an average weight loss of over 15 kg.
The treatment is designed to be taken at a similar time once per week, with each pen lasting for 4 weeks. Doses start low and are titrated slowly over several months to reduce side effects and help your body get used to the medication.
Wegovy works by activating GLP-1 receptors, which play a key role in appetite and digestion. GLP-1 is a hormone your gut naturally releases after meals. It sends signals to the brain to say you're full and slows the rate at which food leaves your stomach. The treatment can also help stabilise blood sugar levels. By mimicking this hormone, semaglutide strengthens these natural signals, making it easier to feel satisfied with smaller meals.
This hormone-based action helps you naturally eat fewer calories without feeling overly hungry or deprived. Many people notice their cravings (especially sugary or high-calorie foods) become much easier to manage. Wegovy also helps steady your blood sugar levels, which can reduce energy dips and make healthier eating feel more achievable. Because it works with your body’s own appetite signals, it supports sustainable habits over time rather than offering a temporary fix.
Wegovy has repeatedly demonstrated its ability to achieve clinically meaningful weight loss when used in conjunction with healthy lifestyle choices. Its effectiveness has been shown in the STEP programme, a series of large-scale clinical trials. The STEP-1 trial, for example, found that the average Wegovy weight loss was around 15% over 68 weeks, with some individuals losing up to 17%.
Other key findings from the STEP programme included that more than 80% of participants lost at least 5% of their weight, an extremely meaningful health benefit in itself. Almost 70% of Wegovy users achieved a 10% or greater weight loss, while over half lost at least 15%. Side effects were mostly gut-related (nausea, diarrhoea), though they were typically mild to moderate and tended to improve over time.
Not only does Wegovy work for weight loss, but it is also the only treatment of its kind approved in the UK for individuals with established cardiovascular disease. This came as the result of a multinational study which found that semaglutide lowered the risk of major adverse cardiovascular events (such as myocardial infarction and stroke) by 20%. This is compared to just 8% in patients who took a placebo.
Wegovy’s active ingredient, semaglutide, gets to work immediately after administering the first dose. You may feel fuller and notice a reduction in food noise after a few days; however, it can take several months for significant weight loss to occur. As a result, Wegovy should be considered part of a long-term programme rather than a short-term solution.
Wegovy is suitable for long-term use, provided you’re still noticing the benefits. It is important to use this time to develop lasting lifestyle changes that will continue even after treatment ends. This is especially important considering trials have shown that much of the weight lost while taking Wegovy can return if healthy habits are abandoned.
The STEP-4 Trial noted a mean change in body weight of 17.4% after 68 weeks.
This calculator is provided for illustrative purposes only, and the results are not guaranteed. Everyone’s weight loss journey is unique.
Promising Start
Clinical research has found that, after 12 weeks, Wegovy weight loss could be around 6% of your starting body weight. This is compared to less than 2% with a placebo.
Making Progress
After 6 months, you could expect to lose an average of 12.3kg with Wegovy weight loss injections. Some 54.9% of people lost at least 10% of their starting weight at this point.
Real Results
Spending a year on Wegovy could result in a 17.6% drop in weight, according to one study. Some 43.3% of patients even reported losing more than 20% body weight.
In the UK, Wegovy is approved for adults who are obese (BMI ≥30) or overweight (BMI ≥27) and have weight-related health problems such as high blood pressure or prediabetes.
Before prescribing, our clinicians will assess your medical history and suitability to ensure Wegovy is right for you.
Wegovy is given as a once-weekly injection under the skin (subcutaneously). The most common areas to inject are your belly, thigh or upper arm. Each pen contains a single weekly dose, making it easy to stay on track. You simply choose a weekly “Wegovy day” and inject on the same day every week.
To reduce irritation, rotate injection sites each week. Pens should be stored in the fridge before the first use, but once in use, they can be kept at room temperature for a limited period.
Wegovy treatment starts low and increases gradually to help minimise side effects. The typical schedule begins at 0.25 mg once weekly, increasing every four weeks until reaching the maintenance dose of 2.4 mg once weekly. Your prescriber will guide your dose depending on how well you tolerate dose increases.
If you miss a dose of Wegovy and your next scheduled injection is more than 48 hours away, take the missed dose as soon as possible. Otherwise, skip the missed dose and take the next one on your regularly scheduled day. Do not attempt to take more than the prescribed dose. If you inject too much Wegovy, speak to a GP or go to your nearest hospital.
The highest doses of Wegovy are considered the most effective for weight loss; however, it’s essential to start on a lower strength so your body can adapt to the medication and build tolerance. Taking it slowly and giving yourself time to build healthy eating and exercise habits is crucial for achieving sustainable weight loss.
Although Wegovy injections are generally well tolerated, side effects can still occur for some people, while others may not experience anything at all. Here are some potential Wegovy side effects to look out for:
Headache
Nausea
Vomiting
Constipation
Diarrhoea
Flatulence
Stomach inflammation
Injection site reactions
Heartburn
Change in taste
Feeling weak or tired
Fast heartbeat
Delay in stomach emptying
Low blood sugar
Increase in pancreatic enzymes
Increased level of bilirubin in the blood
Inflamed pancreas
Kidney or bladder stones
Hip fractures
Allergic reactions
Complications of diabetic eye disease
It’s important to be aware that the above table is not an exhaustive list of Wegovy side effects. A more comprehensive breakdown can be found within the Patient Information Leaflet.
Yes, common Wegovy side effects are mild in nature and tend to go away once your body becomes accustomed to the medication. Side effects tend to present themselves as treatment starts or when the dosage increases
There are several steps you can take to reduce the impact of Wegovy side effects. These include avoiding high-fat or greasy foods, keeping well-hydrated, and eating smaller, more frequent meals. You can also use over-the-counter pain relief.
If you’re unsure about where to buy Wegovy in the UK and what your options are, Weight Loss Journey is here to help.
Yes, you can order Wegovy online from reputable companies such as Weight Loss Journey. Simply provide some medical and lifestyle information, and our clinicians can determine whether the treatment is right for you
Yes, Wegovy is classified as a prescription-only medication (POM) and so cannot be bought over the counter. You can obtain a Wegovy prescription from an online service such as Weight Loss Journey or from a specialist clinic.
Yes, you can get Wegovy on the NHS. However, the treatment is subject to more stringent eligibility criteria, and supply may be limited. A face-to-face consultation will also be required before a prescription can be issued.
Weight Loss Journey is proud to offer a range of treatments designed to help you reach your goals.
No, Wegovy is not the same as Ozempic. While they both have the same ingredient, semaglutide, only Wegovy is licensed for weight loss in the UK and is therefore more effective for this purpose. Ozempic, meanwhile, is prescribed for type 2 diabetes. The treatments also have different dosage schedules and cannot be used interchangeably.
Yes. Research shows that most of the weight people lose on Wegovy comes from body fat rather than muscle, especially around the stomach area. Wegovy reduces appetite and calorie intake, encouraging your body to use stored fat for energy. This process is gradual but steady, especially at higher doses.
Clinical studies also show noticeable reductions in waist circumference, which is often considered a key sign of losing stomach fat.
Wegovy isn’t suitable for everyone. It should not be used by people with:
Type 1 diabetes
Pancreatitis
Certain rare thyroid cancers, like medullary thyroid carcinoma (MTC) or conditions such as MEN2 syndrome.
It’s also not recommended during pregnancy or while breastfeeding. Your clinician will review your medical history to ensure the treatment is safe.
Wegovy doesn’t directly interfere with the effectiveness of most contraceptive methods (including the combined pill, patch, implant or hormonal coils). However, side effects like nausea or vomiting can impact how well oral pills are absorbed. Non-oral contraceptives are not affected
Yes, Wegovy has several proven health benefits beyond weight reduction. Studies show improvements in blood sugar levels, cholesterol profiles and blood pressure - all of which support better heart and metabolic health. Many people also report reduced cravings and better portion control. For people with prediabetes, Wegovy may reduce the risk of developing type 2 diabetes.
When determining whether Mounjaro or Wegovy is best for weight loss, several factors should be considered. Mounjaro is the most effective, with a potential weight loss of 22.5% compared to around 17% on Wegovy. On the other hand, Wegovy may be more cost-effective, while still offering considerable benefits for those looking to lose weight.
If you’re unsure about whether Mounjaro or Wegovy is the better option for you, our specialist clinicians are here to help. Simply complete our online medical questionnaire, and they will review your information and recommend the most suitable treatment for your circumstances.
Yes, you can drink alcohol on Wegovy, but you should do so in moderation. There are no direct interactions or warnings regarding mixing Wegovy and alcohol, but taking both together could increase the severity of Wegovy side effects such as nausea and vomiting. Alcohol can also cause dehydration and lower blood glucose levels, a potential problem if you have diabetes.
On a wider note, alcohol is usually extremely dense in calories and can also encourage poor food choices. These factors can seriously undermine your weight loss progress if left unchecked.
No, it’s not recommended to take Wegovy while pregnant or if you plan to become pregnant. The same is true if you are breastfeeding, as it’s not known if semaglutide passes into breast milk. A review of clinical studies involving humans and animals concluded that there was evidence suggesting that GLP-1 agonists could affect fetal weight, growth and skeletal ossification.
If you’re currently using Wegovy injections for weight loss, it’s recommended that you stop taking the medication two months before you plan on becoming pregnant
Before opening, store your Wegovy injection pens in the refrigerator at 2°C to 8°C. During use, you can keep them for 6 weeks when stored below 308°C or in the fridge. Keep the pens away from the cooling element and do not freeze. Leave the pen cap on to protect from light, and do not use it after the expiry date.
It’s essential to keep Wegovy weight loss injections out of the sight and reach of children and animals. Do not use the medication if the solution is not clear or colourless, and never put it down the drain or into household waste.
While there’s no best time to take Wegovy injections for weight loss, the key to success is consistency. Try to administer the medication around the same time every week and create a schedule that suits your lifestyle. If you find yourself struggling to remember when to use Wegovy, consider pairing it with a weekly activity or setting an alarm.
You can change the day you take Wegovy if you’re having difficulty sticking to your original routine. You can do this provided your last dose was administered at least 2 days beforehand.
When you stop taking Wegov, you may find that your appetite returns to its previous level. Although you won’t get any withdrawal symptoms, you may experience some side effects as your body adjusts. Some clinical studies have found that stopping Wegovy can lead to weight regain of about two-thirds, though there are ways to try to prevent this.
To minimise weight regain after stopping Wegovy, keep up your diet and exercise routine. Be sure to manage portion sizes and limit your intake of processed foods. Drink plenty of fluids and try to avoid sugary drinks.
Yes, you can switch to Wegovy from other weight loss treatments, such as tablets or injections . If you’re considering changing medications, it’s important to consult a clinician or a specialist medical professional before doing so. They will assess your reasons for making the switch and help you determine whether semaglutide is suitable for your circumstances.
Yes, if you’re taking Ozempic and weight loss is your primary goal, switching to Wegovy would be beneficial. Wegovy is the only of the two medications licensed for weight loss in the UK, while Ozempic is approved for diabetes. Wegovy is considered more effective due to its higher maximum dose and clinical trials showing a greater weight loss.
Just as with any medication change, switching from Ozempic to Wegovy requires approval from a clinician or healthcare professional. This is to determine whether Wegovy is right for you and if you’re eligible for the treatment.
Yes, there are several alternatives to Wegovy injections for weight loss. Each of these has its own potential benefits and mechanisms of action, so it’s important to consult your clinician to determine which option is best for you.
At Weight Loss Journey, we provide the following treatments:
Mounjaro: A dual-action weight loss injection that contains tirzepatide as its active ingredient. Clinical trials have found that Mounjaro can lead to a 20.9% weight loss after 36 weeks of treatment.
Nevolat: Formerly known as Saxenda, Nevolat contains the active ingredient liraglutide. It is administered once daily and can result in a weight loss of around 15%.
Mysimba: Originally used to treat addiction, the ingredients in Mysimba tablets could help you lose around 3.67kg from your starting body weight.
Orlistat: Containing the active ingredient of the same name, Orlistat capsules support weight loss by blocking the absorption of 30% of the fat you consume. This helps facilitate a calorie deficit.
Xenical: The branded version of Orlistat, Xenical tablets were shown in clinical trials to result in a 2.89kg greater weight loss than placebos.
Alli: Available over the counter, Alli contains 60 mg of the active ingredient orlistat. It also supports weight loss by blocking fat absorption, this time by 25%
Here are some additional resources to help you learn more about Mounjaro, how it works, and clinical studies related to the drug.
Novo Nordisk
Novo Nordisk
Novo Nordisk
MotherToBaby (2023)
SpringerNature (2024)
Annals of Internal Medicine (2005)
